Uji aktivitas antibakteri ekstrak bawang putih dan bawang hitam siung tunggal (Allium sativum) terhadap Acinetobacter baumannii

Authors

  • Anzas Niam Saputra Departement of Microbiology, Faculty of Medicine, Universitas Tanjungpura
  • Mahyarudin Mahyarudin Departemen Mikrobiologi (Fakultas Kedokteran, Universitas Tanjungpura)
  • Syarifah Nurul Yanti Rizki Syahab Asseggaf Departemen Farmakologi (Fakultas Kedokteran, Universitas Tanjungpura)

DOI:

https://doi.org/10.31571/saintek.v12i1.5989

Keywords:

Bawang putih siung tunggal, Bawang hitam siung tunggal, Antibakteri, Acinetobacter baumannii

Abstract

Latar Belakang: Kasus resistensi obat telah ditemukan dalam pengobatan penyakit yang disebabkan oleh bakteri Acinetobacter baumannii. Bawang putih dan bawang hitam siung tunggal diduga dapat menjadi obat antibakteri karena mengandung metabolit sekunder seperti alkaloid, flavonoid, fenolik, saponin, tanin, dan senyawa organosulfur yang mampu menghambat pertumbuhan bakteri. Tujuan: Mengetahui aktivitas antibakteri ekstrak bawang putih siung tunggal dan bawang hitam siung tunggal terhadap Acinetobacter baumannii. Metode: Jenis penelitian ini adalah penelitian experiment dengan rancangan penelitian post-test only control group design. Metode difusi cakram Kirby-Bauer digunakan untuk uji antibakteri dan metode kualitatif dengan reaksi reagen spesifik digunakan untuk analisis fitokimia. Hasil: Zona hambat yang terbentuk oleh kedua ekstrak didapatkan mulai dari konsentrasi 50%. Rata-rata diameter zona hambat yang terbentuk oleh ekstrak etanol bawang putih siung tunggal konsentrasi 50%, 75%, dan 100% adalah 7,5 mm (sedang), 7,87 mm (sedang), dan 9,8 mm (sedang). Sedangkan rata-rata diameter ekstrak etanol bawang hitam siung tunggal konsentrasi 50%, 75%, dan 100% adalah 8,77 mm (sedang), 12,03 mm (kuat), dan 12,5 mm (kuat). Analisis fitokimia menunujukkan ekstrak etanol bawang putih siung tunggal mengandung alkaloid, flavonoid, saponin, tanin, dan sulfur. Sedangkan ekstrak etanol bawang hitam siung tunggal mengandung alkaloid, flavonoid, fenolik, saponin, tanin, dan sulfur. Kesimpulan: Aktivitas antibakteri ekstrak bawang hitam siung tunggal lebih tinggi dibandingkan ekstrak bawang putih siung tunggal.

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Published

2023-06-30

How to Cite

Saputra, A. N., Mahyarudin, M., & Asseggaf, S. N. Y. R. S. (2023). Uji aktivitas antibakteri ekstrak bawang putih dan bawang hitam siung tunggal (Allium sativum) terhadap Acinetobacter baumannii. Jurnal Pendidikan Informatika Dan Sains, 12(1), 256–265. https://doi.org/10.31571/saintek.v12i1.5989

Issue

Vol. 12 No. 1 (2023): Jurnal Pendidikan Informatika dan Sains

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